The provenance of Middle Jurassic-Cretaceous sedimentary rocks deposited in the southern Peruvian Arequipa Basin has been investigated based on the measurement of 41 Sr-Sm-Nd isotopic compositions of sedimentary rocks, 993 U-Pb zircons ages, and 202 Lu-Hf zircon isotope data. The Middle Jurassic units are dominated by Brazilian/Pampean and Grenville/Sunsas and have juvenile to evolved Hf isotopic compositions of Permian zircons. These are consistent with an Eastern Cordillera (EC) provenance. In contrast, the Late Jurassic Labra Formation presents the first appearance of Triassic-Jurassic zircons and an increase in Famatinian zircons thus suggesting a mixed provenance from the EC and/or Altiplano and the Coastal Cordillera (CC). The Gramadal Formation shows older U-Pb zircon ages, which reflect a major contribution from Precambrian sources either from the Amazon craton or the EC thus implying a change in provenance. Another change in provenance is documented for the Hualhuani Formation with sources located both in the CC and EC. Finally, the Santonian Chilcane Formation is characterized by a large contribution of Cretaceous to Famatinian zircons indicating that it was mainly sourced from the CC. Our provenance dataset associated with the depositional setting of the Middle Jurassic to Early Cretaceous formations and the cumulative curves of zircon age distribution, indicate that the Arequipa Basin was not a back-arc setting but rather a rift-like setting. Contrary to the older formations, the Chilcane Formation is dominated by contributions from the CC in a retroarc foreland basin setting. This statement further implies that the Andean basin located eastward of the volcanic arc had evolved directly from a rift to a retroarc foreland basin and implies that the control of Andean subduction on these basins might be much younger than previously thought.
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