TY - JOUR
T1 - SEOM clinical guideline on hereditary colorectal cancer (2019)
AU - Guillén-Ponce, C.
AU - Lastra, E.
AU - Lorenzo-Lorenzo, I.
AU - Martín Gómez, T.
AU - Morales Chamorro, R.
AU - Sánchez-Heras, A. B.
AU - Serrano, R.
AU - Soriano Rodríguez, M. C.
AU - Soto, J. L.
AU - Robles, L.
N1 - Publisher Copyright:
© 2020, The Author(s).
PY - 2020/2/1
Y1 - 2020/2/1
N2 - In the last 2 decades, clinical genetics on hereditary colorectal syndromes has shifted from just a molecular characterization of the different syndromes to the estimation of the individual risk of cancer and appropriate risk reduction strategies. In the last years, new specific therapies for some subgroups of patients have emerged as very effective alternatives. At the same time, germline multigene panel testing by next-generation sequencing (NGS) technology has become the new gold standard for molecular genetics.
AB - In the last 2 decades, clinical genetics on hereditary colorectal syndromes has shifted from just a molecular characterization of the different syndromes to the estimation of the individual risk of cancer and appropriate risk reduction strategies. In the last years, new specific therapies for some subgroups of patients have emerged as very effective alternatives. At the same time, germline multigene panel testing by next-generation sequencing (NGS) technology has become the new gold standard for molecular genetics.
KW - Adenomatous polyposis
KW - Colon cancer
KW - Hereditary colorectal cancer
KW - Lynch syndrome
UR - http://www.scopus.com/inward/record.url?scp=85078418910&partnerID=8YFLogxK
U2 - 10.1007/s12094-019-02272-y
DO - 10.1007/s12094-019-02272-y
M3 - Artículo
C2 - 31981079
AN - SCOPUS:85078418910
SN - 1699-048X
VL - 22
SP - 201
EP - 212
JO - Clinical and Translational Oncology
JF - Clinical and Translational Oncology
IS - 2
ER -