Understanding Risk Factors for Poor Outcomes in a Multiethnic Longitudinal Cohort: The LUMINA (Lupus in Minorities: Nature vs. Nurture) Experience (LUMINA LXXXII)

Luis Alonso González, Guillermo J. Pons-Estel, Sergio M.A. Toloza, Manuel Francisco Ugarte-Gil, Graciela S. Alarcón

Resultado de la investigación: Contribución a una revistaArtículo de revisiónrevisión exhaustiva

Resumen

The Lupus in Minorities: Nature Vs Nurture (LUMINA) cohort has placed Hispanics on the lupus map in the United States. Texan Hispanic and African American patients experience, overall, worse outcomes than the Caucasian and Puerto Rican Hispanic patients. The genetic component of ethnicity is important early in the disease course whereas socioeconomic factors become more important subsequently. The role of hydroxychloroquine in preventing damage accrual and reducing mortality in lupus patients is a major contribution of LUMINA.

Idioma originalInglés
Páginas (desde-hasta)55-64
Número de páginas10
PublicaciónRheumatic Disease Clinics of North America
Volumen47
N.º1
DOI
EstadoPublicada - feb 2021

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© 2020 Elsevier Inc.

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